Metal-polymer composites for a new generation of heart valves

The aim of the presented project is to minimize the formation of life-threatening thromboembolism in the pulsatory heart support chamber, by using a new biomimetic heart valve based on metal-polymer composites. Heart prostheses are dedicated to support the heart of patients with late-stage heart disease. They are dedicated to therapy related to self-regeneration or as a bridge for transplantation. In the future, they will be able to help with heart attack gene therapy. Systems with mechanical valves generate plate activation through shear stresses. This is due to the narrow gap between the petal and the ring. Composite materials and new valve design can minimize this problem.

Injected polyurethane with a metallic, titanium insert combines optimal microscale flexibility with macro-stiffness to ensure proper mechanical function of the valve. Transnational added value consists in:

  1. heart valve design for optimal blood flow,
  2. covering valve components with hemo-bio-functional coatings,
  3. developing a dedicated polymer injection method,
  4. study on an artificial patient model.

Meet the presenter:

Roman Major, Institute of Metallurgy and Materials Engineering Aleksander Krupkowski Polish Academy of Sciences in Krakow; E: rmajor1 Poczt.wp.pl